Cargando…
Validation, kinetic modeling, and test-retest reproducibility of [(18)F]SynVesT-1 for PET imaging of synaptic vesicle glycoprotein 2A in mice
Alterations in synaptic vesicle glycoprotein 2 A (SV2A) have been associated with several neuropsychiatric and neurodegenerative disorders. Therefore, SV2A positron emission tomography (PET) imaging may provide a unique tool to investigate synaptic density dynamics during disease progression and aft...
Autores principales: | Bertoglio, Daniele, Zajicek, Franziska, Lombaerde, Stef De, Miranda, Alan, Stroobants, Sigrid, Wang, Yuchuan, Dominguez, Celia, Munoz-Sanjuan, Ignacio, Bard, Jonathan, Liu, Longbin, Verhaeghe, Jeroen, Staelens, Steven |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536120/ https://www.ncbi.nlm.nih.gov/pubmed/35570828 http://dx.doi.org/10.1177/0271678X221101648 |
Ejemplares similares
-
Kinetic Modelling and Test–Retest Reproducibility for the Dopamine D(1)R Radioligand [(11)C]SCH23390 in Healthy and Diseased Mice
por: Bertoglio, Daniele, et al.
Publicado: (2020) -
Organocatalytic
Asymmetric Synthesis of SynVesT-1,
a Synaptic Density Positron Emission Tomography Imaging Agent
por: McErlain, Holly, et al.
Publicado: (2022) -
Lower synaptic density associated with gaming disorder: an (18)F-SynVesT-1 PET imaging study
por: Hou, Jiale, et al.
Publicado: (2023) -
Synaptic Vesicle Glycoprotein 2A Is Affected in the Central Nervous System of Mice with Huntington Disease and in the Brain of a Human with Huntington Disease Postmortem
por: Bertoglio, Daniele, et al.
Publicado: (2022) -
Preliminary Assessment of Reference Region Quantification and Reduced Scanning Times for [(18)F]SynVesT-1 PET in Parkinson's Disease
por: Smart, Kelly, et al.
Publicado: (2023)