Pathway-based Approach Reveals Differential Sensitivity to E2F1 Inhibition in Glioblastoma

Analysis of tumor gene expression is an important approach for the classification and identification of therapeutic vulnerabilities. However, targeting glioblastoma (GBM) based on molecular subtyping has not yet translated into successful therapies. Here, we present an integrative approach based on...

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Detalles Bibliográficos
Autores principales: Alvarado, Alvaro G., Tessema, Kaleab, Muthukrishnan, Sree Deepthi, Sober, Mackenzie, Kawaguchi, Riki, Laks, Dan R., Bhaduri, Aparna, Swarup, Vivek, Nathanson, David A., Geschwind, Daniel H., Goldman, Steven A., Kornblum, Harley I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536135/
https://www.ncbi.nlm.nih.gov/pubmed/36213002
http://dx.doi.org/10.1158/2767-9764.CRC-22-0003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536135/
https://www.ncbi.nlm.nih.gov/pubmed/36213002
http://dx.doi.org/10.1158/2767-9764.CRC-22-0003

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