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Base-promoted highly efficient synthesis of nitrile-substituted cyclopropanes via Michael-initiated ring closure

A convenient and efficient annulation reaction has been developed for the general synthesis of dinitrile-substituted cyclopropanes in moderate to excellent yields. A variety of 2-arylacetonitriles and α-bromoennitriles were compatible under the standard conditions. The reaction was achieved through...

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Detalles Bibliográficos
Autores principales: Ye, Min, Xu, Fan, Bai, Yun, Zhang, Fanglian, Wang, Wenjia, Qian, Yiping, Chen, Zhengwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536251/
https://www.ncbi.nlm.nih.gov/pubmed/36320497
http://dx.doi.org/10.1039/d2ra05393d