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NR1D1 controls skeletal muscle calcium homeostasis through myoregulin repression

The sarcoplasmic reticulum (SR) plays an important role in calcium homeostasis. SR calcium mishandling is described in pathological conditions, such as myopathies. Here, we investigated whether the nuclear receptor subfamily 1 group D member (NR1D1, also called REV-ERBα) regulates skeletal muscle SR...

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Detalles Bibliográficos
Autores principales: Boulinguiez, Alexis, Duhem, Christian, Mayeuf-Louchart, Alicia, Pourcet, Benoit, Sebti, Yasmine, Kondratska, Kateryna, Montel, Valérie, Delhaye, Stéphane, Thorel, Quentin, Beauchamp, Justine, Hebras, Aurore, Gimenez, Marion, Couvelaere, Marie, Zecchin, Mathilde, Ferri, Lise, Prevarskaya, Natalia, Forand, Anne, Gentil, Christel, Ohana, Jessica, Piétri-Rouxel, France, Bastide, Bruno, Staels, Bart, Duez, Helene, Lancel, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536258/
https://www.ncbi.nlm.nih.gov/pubmed/35917173
http://dx.doi.org/10.1172/jci.insight.153584