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Low-dose IL-2 shapes a tolerogenic gut microbiota that improves autoimmunity and gut inflammation

Gut microbiota dysbiosis is associated with inflammatory bowel diseases and with cardiometabolic, neurological, and autoimmune diseases. Gut microbiota composition has a direct effect on the immune system, and vice versa, and it has a particular effect on Treg homeostasis. Low-dose IL-2 (IL-2(LD)) s...

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Detalles Bibliográficos
Autores principales: Tchitchek, Nicolas, Nguekap Tchoumba, Otriv, Pires, Gabriel, Dandou, Sarah, Campagne, Julien, Churlaud, Guillaume, Fourcade, Gwladys, Hoffmann, Thomas W., Strozzi, Francesco, Gaal, Camille, Bonny, Christophe, Le Chatelier, Emmanuelle, Erlich, Stanislav Dusko, Sokol, Harry, Klatzmann, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536277/
https://www.ncbi.nlm.nih.gov/pubmed/35917175
http://dx.doi.org/10.1172/jci.insight.159406