Targeting extracellular matrix remodeling sensitizes glioblastoma to ionizing radiation

BACKGROUND: The median survival of Glioblastoma multiforme (GBM) patients is 14+ months due to poor responses to surgery and chemoradiation. Means to counteract radiation resistance are therefore highly desirable. We demonstrate the membrane bound matrix metalloproteinase MT1-MMP promotes resistance...

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Detalles Bibliográficos
Autores principales: Thakur, Varsha, Thakur, Vijay S, Aguila, Brittany, Slepak, Tatiana I, Wang, Man, Song, Wei, Konai, Mohini, Mobashery, Shahriar, Chang, Mayland, Rana, Ayush B, Wang, Dazhi, de Freitas, Juliano Tiburcio, Humayun Gultekin, Sakir, Welford, Scott M, Ivan, Michael E, Bedogni, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536293/
https://www.ncbi.nlm.nih.gov/pubmed/36212741
http://dx.doi.org/10.1093/noajnl/vdac147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536293/
https://www.ncbi.nlm.nih.gov/pubmed/36212741
http://dx.doi.org/10.1093/noajnl/vdac147

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