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Targeting extracellular matrix remodeling sensitizes glioblastoma to ionizing radiation
BACKGROUND: The median survival of Glioblastoma multiforme (GBM) patients is 14+ months due to poor responses to surgery and chemoradiation. Means to counteract radiation resistance are therefore highly desirable. We demonstrate the membrane bound matrix metalloproteinase MT1-MMP promotes resistance...
Autores principales: | Thakur, Varsha, Thakur, Vijay S, Aguila, Brittany, Slepak, Tatiana I, Wang, Man, Song, Wei, Konai, Mohini, Mobashery, Shahriar, Chang, Mayland, Rana, Ayush B, Wang, Dazhi, de Freitas, Juliano Tiburcio, Humayun Gultekin, Sakir, Welford, Scott M, Ivan, Michael E, Bedogni, Barbara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536293/ https://www.ncbi.nlm.nih.gov/pubmed/36212741 http://dx.doi.org/10.1093/noajnl/vdac147 |
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