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Programmed death ligand 1 gene silencing in murine glioma models reveals cell line-specific modulation of tumor growth in vivo

BACKGROUND: Glioblastoma is the most common brain tumor in adults and virtually incurable. Therefore, new therapeutic strategies are urgently needed. Immune checkpoint inhibition has not shown activity in various phase III trials and intra- as well as intertumoral expression of programmed death liga...

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Detalles Bibliográficos
Autores principales: Blomberg, Evelina, Silginer, Manuela, Roth, Patrick, Weller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536295/
https://www.ncbi.nlm.nih.gov/pubmed/36212740
http://dx.doi.org/10.1093/noajnl/vdac148