Effect of chronic unpredicted mild stress-induced depression on clopidogrel pharmacokinetics in rats

BACKGROUND: Clopidogrel is widely used to prevent and treat cardiovascular atherosclerosis and thrombosis. However, disturbance in the expression and activity of liver cytochrome metabolic enzymes significantly changes clopidogrel efficacy. Therefore, the effect of chronic unpredictable mild stress...

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Detalles Bibliográficos
Autores principales: Jiang, Xueyao, Wu, Jing, Tan, Boyu, Yan, Sulan, Deng, Nan, Wei, Hongyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2022
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536304/
https://www.ncbi.nlm.nih.gov/pubmed/36213502
http://dx.doi.org/10.7717/peerj.14111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536304/
https://www.ncbi.nlm.nih.gov/pubmed/36213502
http://dx.doi.org/10.7717/peerj.14111

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