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Topical Nanoemulsion of a Runt-related Transcription Factor 1 Inhibitor for the Treatment of Pathologic Ocular Angiogenesis

PURPOSE: To test the efficacy of runt-related transcription factor 1 (RUNX1) inhibition with topical nanoemulsion containing Ro5-3335 (eNano-Ro5) in experimental ocular neovascularization. DESIGN: Preclinical experimental study. PARTICIPANTS: In vitro primary culture human retinal endothelial cell (...

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Detalles Bibliográficos
Autores principales: Delgado-Tirado, Santiago, Gonzalez-Buendia, Lucia, An, Miranda, Amarnani, Dhanesh, Isaacs-Bernal, Daniela, Whitmore, Hannah, Arevalo-Alquichire, Said, Leyton-Cifuentes, David, Ruiz-Moreno, Jose M., Arboleda-Velasquez, Joseph F., Kim, Leo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536424/
https://www.ncbi.nlm.nih.gov/pubmed/36213726
http://dx.doi.org/10.1016/j.xops.2022.100163