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Synthesis of (+)-ribostamycin by catalytic, enantioselective hydroamination of benzene

Aminoglycosides (AGs) represent a large group of pseudoglycoside natural products, in which several different sugar moieties are harnessed to an aminocyclitol core. AGs constitute a major class of antibiotics that target the prokaryotic ribosome of many problematic pathogens. Hundreds of AGs have be...

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Detalles Bibliográficos
Autores principales: Ungarean, Chad N., Galer, Petra, Zhang, Yu, Lee, Ken S., Ngai, Justin M., Lee, Sungjong, Liu, Peng, Sarlah, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536474/
https://www.ncbi.nlm.nih.gov/pubmed/36213185
http://dx.doi.org/10.1038/s44160-022-00080-x