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Design of immunogens for eliciting antibody responses that may protect against SARS-CoV-2 variants

The rise of SARS-CoV-2 variants and the history of outbreaks caused by zoonotic coronaviruses point to the need for next-generation vaccines that confer protection against variant strains. Here, we combined analyses of diverse sequences and structures of coronavirus spikes with data from deep mutati...

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Detalles Bibliográficos
Autores principales: Wang, Eric, Chakraborty, Arup K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536555/
https://www.ncbi.nlm.nih.gov/pubmed/36156540
http://dx.doi.org/10.1371/journal.pcbi.1010563