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Design of immunogens for eliciting antibody responses that may protect against SARS-CoV-2 variants
The rise of SARS-CoV-2 variants and the history of outbreaks caused by zoonotic coronaviruses point to the need for next-generation vaccines that confer protection against variant strains. Here, we combined analyses of diverse sequences and structures of coronavirus spikes with data from deep mutati...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536555/ https://www.ncbi.nlm.nih.gov/pubmed/36156540 http://dx.doi.org/10.1371/journal.pcbi.1010563 |