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A whole genome sequencing approach to anterior cruciate ligament rupture–a twin study in two unrelated families

Predisposition to anterior cruciate ligament (ACL) rupture is multi-factorial, with variation in the genome considered a key intrinsic risk factor. Most implicated loci have been identified from candidate gene-based approach using case-control association settings. Here, we leverage a hypothesis-fre...

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Detalles Bibliográficos
Autores principales: Feldmann, Daneil, Bope, Christian D., Patricios, Jon, Chimusa, Emile R., Collins, Malcolm, September, Alison V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536556/
https://www.ncbi.nlm.nih.gov/pubmed/36201451
http://dx.doi.org/10.1371/journal.pone.0274354