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Feasibility of a novel non-invasive swab technique for serial whole-exome sequencing of cervical tumors during chemoradiation therapy

BACKGROUND: Clinically relevant genetic predictors of radiation response for cervical cancer are understudied due to the morbidity of repeat invasive biopsies required to obtain genetic material. Thus, we aimed to demonstrate the feasibility of a novel noninvasive cervical swab technique to (1) coll...

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Detalles Bibliográficos
Autores principales: Bronk, Julianna K., Kapadia, Chiraag, Wu, Xiaogang, Chapman, Bhavana V., Wang, Rui, Karpinets, Tatiana V., Song, Xingzhi, Futreal, Andrew M., Zhang, Jianhua, Klopp, Ann H., Colbert, Lauren E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536567/
https://www.ncbi.nlm.nih.gov/pubmed/36201462
http://dx.doi.org/10.1371/journal.pone.0274457