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Effects of replication domains on genome-wide UV-induced DNA damage and repair

Nucleotide excision repair is the primary repair mechanism that removes UV-induced DNA lesions in placentals. Unrepaired UV-induced lesions could result in mutations during DNA replication. Although the mutagenesis of pyrimidine dimers is reasonably well understood, the direct effects of replication...

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Detalles Bibliográficos
Autores principales: Huang, Yanchao, Azgari, Cem, Yin, Mengdie, Chiou, Yi-Ying, Lindsey-Boltz, Laura A., Sancar, Aziz, Hu, Jinchuan, Adebali, Ogun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536635/
https://www.ncbi.nlm.nih.gov/pubmed/36155646
http://dx.doi.org/10.1371/journal.pgen.1010426