Clinically Relevant Changes for Cognitive Outcomes in Preclinical and Prodromal Cognitive Stages: Implications for Clinical Alzheimer Trials

BACKGROUND AND OBJECTIVES: Identifying a clinically meaningful change in cognitive test score is essential when using cognition as an outcome in clinical trials. This is especially relevant because clinical trials increasingly feature novel composites of cognitive tests. Our primary objective was to...

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Detalles Bibliográficos
Autores principales: Borland, Emma, Edgar, Chris, Stomrud, Erik, Cullen, Nicholas, Hansson, Oskar, Palmqvist, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536741/
https://www.ncbi.nlm.nih.gov/pubmed/35835560
http://dx.doi.org/10.1212/WNL.0000000000200817

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536741/
https://www.ncbi.nlm.nih.gov/pubmed/35835560
http://dx.doi.org/10.1212/WNL.0000000000200817

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