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Clinically Relevant Changes for Cognitive Outcomes in Preclinical and Prodromal Cognitive Stages: Implications for Clinical Alzheimer Trials
BACKGROUND AND OBJECTIVES: Identifying a clinically meaningful change in cognitive test score is essential when using cognition as an outcome in clinical trials. This is especially relevant because clinical trials increasingly feature novel composites of cognitive tests. Our primary objective was to...
Autores principales: | Borland, Emma, Edgar, Chris, Stomrud, Erik, Cullen, Nicholas, Hansson, Oskar, Palmqvist, Sebastian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536741/ https://www.ncbi.nlm.nih.gov/pubmed/35835560 http://dx.doi.org/10.1212/WNL.0000000000200817 |
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