Investigating the possible mechanisms of pirfenidone to be targeted as a promising anti-inflammatory, anti-fibrotic, anti-oxidant, anti-apoptotic, anti-tumor, and/or anti-SARS-CoV-2

Pirfenidone (PFD) is a non-peptide synthetic chemical that inhibits the production of transforming growth factor-beta 1 (TGF-β1), tumor necrosis factor-alpha (TNF-α), platelet-derived growth factor (PDGF), Interleukin 1 beta (IL-1β), and collagen 1 (COL1A1), all of which have been linked to the prev...

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Detalles Bibliográficos
Autores principales: Antar, Samar A., Saleh, Mohamed A., Al-Karmalawy, Ahmed A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536875/
https://www.ncbi.nlm.nih.gov/pubmed/36209833
http://dx.doi.org/10.1016/j.lfs.2022.121048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9536875/
https://www.ncbi.nlm.nih.gov/pubmed/36209833
http://dx.doi.org/10.1016/j.lfs.2022.121048

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