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Loss of Zfp335 triggers cGAS/STING-dependent apoptosis of post-β selection thymocytes

Production of a functional peripheral T cell compartment typically involves massive expansion of the bone marrow progenitors that seed the thymus. There are two main phases of expansion during T cell development, following T lineage commitment of double-negative (DN) 2 cells and after successful rea...

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Detalles Bibliográficos
Autores principales: Ratiu, Jeremy J., Barclay, William E., Lin, Elliot, Wang, Qun, Wellford, Sebastian, Mehta, Naren, Harnois, Melissa J., DiPalma, Devon, Roy, Sumedha, Contreras, Alejandra V., Shinohara, Mari L., Wiest, David, Zhuang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537144/
https://www.ncbi.nlm.nih.gov/pubmed/36202870
http://dx.doi.org/10.1038/s41467-022-33610-4