Neutralizing and interfering human antibodies define the structural and mechanistic basis for antigenic diversion

Defining mechanisms of pathogen immune evasion and neutralization are critical to develop potent vaccines and therapies. Merozoite Surface Protein 1 (MSP-1) is a malaria vaccine antigen and antibodies to MSP-1 are associated with protection from disease. However, MSP-1-based vaccines performed poorl...

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Detalles Bibliográficos
Autores principales: Patel, Palak N., Dickey, Thayne H., Hopp, Christine S., Diouf, Ababacar, Tang, Wai Kwan, Long, Carole A., Miura, Kazutoyo, Crompton, Peter D., Tolia, Niraj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537153/
https://www.ncbi.nlm.nih.gov/pubmed/36202833
http://dx.doi.org/10.1038/s41467-022-33336-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537153/
https://www.ncbi.nlm.nih.gov/pubmed/36202833
http://dx.doi.org/10.1038/s41467-022-33336-3

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