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A novel vaccine based on SARS-CoV-2 CD4(+) and CD8(+) T cell conserved epitopes from variants Alpha to Omicron

COVID-19 caused, as of September, 1rst, 2022, 599,825,400 confirmed cases, including 6,469,458 deaths. Currently used vaccines reduced severity and mortality but not virus transmission or reinfection by different strains. They are based on the Spike protein of the Wuhan reference virus, which althou...

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Detalles Bibliográficos
Autores principales: Palatnik-de-Sousa, Iam, Wallace, Zachary S., Cavalcante, Stephany Christiny, Ribeiro, Maria Paula Fonseca, Silva, João Antônio Barbosa Martins, Cavalcante, Rafael Ciro, Scheuermann, Richard H., Palatnik-de-Sousa, Clarisa Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537284/
https://www.ncbi.nlm.nih.gov/pubmed/36202985
http://dx.doi.org/10.1038/s41598-022-21207-2