Consequences of telomere dysfunction in fibroblasts, club and basal cells for lung fibrosis development

TRF1 is an essential component of the telomeric protective complex or shelterin. We previously showed that dysfunctional telomeres in alveolar type II (ATII) cells lead to interstitial lung fibrosis. Here, we study the lung pathologies upon telomere dysfunction in fibroblasts, club and basal cells....

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Detalles Bibliográficos
Autores principales: Piñeiro-Hermida, Sergio, Martínez, Paula, Bosso, Giuseppe, Flores, Juana María, Saraswati, Sarita, Connor, Jane, Lemaire, Raphael, Blasco, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537293/
https://www.ncbi.nlm.nih.gov/pubmed/36202783
http://dx.doi.org/10.1038/s41467-022-32771-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537293/
https://www.ncbi.nlm.nih.gov/pubmed/36202783
http://dx.doi.org/10.1038/s41467-022-32771-6

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