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The ratio of 12α to non-12-hydroxylated bile acids reflects hepatic triacylglycerol accumulation in high-fat diet-fed C57BL/6J mice

In our previous study, enterohepatic 12α-hydroxylated (12α) bile acid (BA) levels were found to be correlated with hepatic triacylglycerol concentration in rats fed high-fat (HF) diet. Since BA composition is diverse depending on animal species, we evaluated whether such a relationship is applicable...

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Detalles Bibliográficos
Autores principales: Iwasaki, Wakana, Yoshida, Ryo, Liu, Hongxia, Hori, Shota, Otsubo, Yuki, Tanaka, Yasutake, Sato, Masao, Ishizuka, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537321/
https://www.ncbi.nlm.nih.gov/pubmed/36202928
http://dx.doi.org/10.1038/s41598-022-20838-9