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A closer look at the synthesis of 2-[(18)F]fluoroethyl tosylate to minimize the formation of volatile side-products

BACKGROUND: 2-[(18)F]Fluoroethyltosylate ([(18)F]FEtOTs) is a well-known (18)F-fluoroalkylating agent widely used to synthesize radiotracers for positron emission tomography. The widespread use of [(18)F]FEtOTs is due in part to its low volatility when compared to other halide and sulfonate building...

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Detalles Bibliográficos
Autores principales: Pijeira, Martha Sahylí Ortega, dos Santos, Sofia Nascimento, Araujo, Yasniel Babi, Lapolli, André Luis, Wandermuren, Marcio Nardelli, Riera, Zalua Rodríguez, Carvalho, Ivone, Elsinga, Philip H., Bernardes, Emerson Soares
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537402/
https://www.ncbi.nlm.nih.gov/pubmed/36201072
http://dx.doi.org/10.1186/s41181-022-00179-8