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The role of extracellular vesicle miRNAs and tRNAs in synovial fibroblast senescence

Extracellular vesicles are mediators of intercellular communication with critical roles in cellular senescence and ageing. In arthritis, senescence is linked to the activation of a pro-inflammatory phenotype contributing to chronic arthritis pathogenesis. We hypothesised that senescent osteoarthriti...

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Detalles Bibliográficos
Autores principales: Wijesinghe, Susanne N., Anderson, James, Brown, Thomas J., Nanus, Dominika E., Housmans, Bas, Green, Jonathan A., Hackl, Matthias, Choi, Katie K., Arkill, Kenton P., Welting, Tim, James, Victoria, Jones, Simon W., Peffers, Mandy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537453/
https://www.ncbi.nlm.nih.gov/pubmed/36213127
http://dx.doi.org/10.3389/fmolb.2022.971621