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A framework for dissecting affinities of multidrug efflux transporter AcrB to fluoroquinolones
Sufficient concentration of antibiotics close to their target is key for antimicrobial action. Among the tools exploited by bacteria to reduce the internal concentration of antibiotics, multidrug efflux pumps stand out for their ability to capture and expel many unrelated compounds out of the cell....
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537517/ https://www.ncbi.nlm.nih.gov/pubmed/36203030 http://dx.doi.org/10.1038/s42003-022-04024-1 |