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Modeling human telencephalic development and autism-associated SHANK3 deficiency using organoids generated from single neural rosettes
Human telencephalon is an evolutionarily advanced brain structure associated with many uniquely human behaviors and disorders. However, cell lineages and molecular pathways implicated in human telencephalic development remain largely unknown. We produce human telencephalic organoids from stem cell-d...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537523/ https://www.ncbi.nlm.nih.gov/pubmed/36202854 http://dx.doi.org/10.1038/s41467-022-33364-z |