Modeling human telencephalic development and autism-associated SHANK3 deficiency using organoids generated from single neural rosettes

Human telencephalon is an evolutionarily advanced brain structure associated with many uniquely human behaviors and disorders. However, cell lineages and molecular pathways implicated in human telencephalic development remain largely unknown. We produce human telencephalic organoids from stem cell-d...

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Detalles Bibliográficos
Autores principales: Wang, Yueqi, Chiola, Simone, Yang, Guang, Russell, Chad, Armstrong, Celeste J., Wu, Yuanyuan, Spampanato, Jay, Tarboton, Paisley, Ullah, H. M. Arif, Edgar, Nicolas U., Chang, Amelia N., Harmin, David A., Bocchi, Vittoria Dickinson, Vezzoli, Elena, Besusso, Dario, Cui, Jun, Cattaneo, Elena, Kubanek, Jan, Shcheglovitov, Aleksandr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537523/
https://www.ncbi.nlm.nih.gov/pubmed/36202854
http://dx.doi.org/10.1038/s41467-022-33364-z

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