Synthesis and anticancer activity of new benzensulfonamides incorporating s-triazines as cyclic linkers for inhibition of carbonic anhydrase IX

Limited presence of hCA IX in normal physiological tissues and their overexpression only in solid hypoxic tumors made this isoform excellent possible target for developing new anticancer agents. We reported designing and synthesis of two novel series of benzenesulfonamides derivatives as hCA IX inhi...

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Detalles Bibliográficos
Autores principales: Zain-Alabdeen, Abdelrahman I., El-Moselhy, Tarek F., Sharafeldin, Nabaweya, Angeli, Andrea, Supuran, Claudiu T., El-Hamamsy, Mervat H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537541/
https://www.ncbi.nlm.nih.gov/pubmed/36202955
http://dx.doi.org/10.1038/s41598-022-21024-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537541/
https://www.ncbi.nlm.nih.gov/pubmed/36202955
http://dx.doi.org/10.1038/s41598-022-21024-7

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