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Amphiphilic aminoglycosides: Modifications that revive old natural product antibiotics
Widely-used Streptomyces-derived antibacterial aminoglycosides have encountered challenges because of antibiotic resistance and toxicity. Today, they are largely relegated to medicinal topical applications. However, chemical modification to amphiphilic aminoglycosides can revive their efficacy again...
Autores principales: | Takemoto, Jon Y., Altenberg, Guillermo A., Poudyal, Naveena, Subedi, Yagya P., Chang, Cheng-Wei T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537547/ https://www.ncbi.nlm.nih.gov/pubmed/36212866 http://dx.doi.org/10.3389/fmicb.2022.1000199 |
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