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Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling

Background: Peritoneal fibrosis (PF) is an intractable complication in patients on long-term peritoneal dialysis (PD). Transforming growth factor-β (TGF-β) is a key pro-fibrogenic factor involved in PD-associated PF, and endoglin, as a coreceptor for TGF-β, plays a role in balancing the TGF-β signal...

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Detalles Bibliográficos
Autores principales: Huang, Qian, Xiao, Rui, Lu, Jing, Zhang, Yao, Xu, Liang, Gao, Jie, Sun, Jing, Wang, Haiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537553/
https://www.ncbi.nlm.nih.gov/pubmed/36210850
http://dx.doi.org/10.3389/fphar.2022.973182