Cargando…

Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling

Background: Peritoneal fibrosis (PF) is an intractable complication in patients on long-term peritoneal dialysis (PD). Transforming growth factor-β (TGF-β) is a key pro-fibrogenic factor involved in PD-associated PF, and endoglin, as a coreceptor for TGF-β, plays a role in balancing the TGF-β signal...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Qian, Xiao, Rui, Lu, Jing, Zhang, Yao, Xu, Liang, Gao, Jie, Sun, Jing, Wang, Haiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537553/ https://www.ncbi.nlm.nih.gov/pubmed/36210850 http://dx.doi.org/10.3389/fphar.2022.973182

Ejemplares similares

TGF-β/Smad Signaling Pathway in Tubulointerstitial Fibrosis
por: Yu, Xiao-Yong, et al.
Publicado: (2022)

Targeting TGF-β Mediated SMAD Signaling for the Prevention of Fibrosis
por: Walton, Kelly L., et al.
Publicado: (2017)

Effects of Nervilia fordii Extract on Pulmonary Fibrosis Through TGF-β/Smad Signaling Pathway
por: Yao, Yufeng, et al.
Publicado: (2021)

Endoglin and TGF-β signaling in glioblastoma
por: Burghardt, Isabel, et al.
Publicado: (2021)

ALK1 regulates the internalization of endoglin and the type III TGF-β receptor
por: Tazat, Keren, et al.
Publicado: (2021)

Blueberry Juice Attenuates Pulmonary Fibrosis via Blocking the TGF-β1/Smad Signaling Pathway
por: Li, Yali, et al.
Publicado: (2022)

Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation
por: Lu, Jing, et al.
Publicado: (2023)

TGF-β/Smad signaling in renal fibrosis
por: Meng, Xiao-Ming, et al.
Publicado: (2015)

Saikosaponin D Inhibits Peritoneal Fibrosis in Rats With Renal Failure by Regulation of TGFβ1/ BMP7 / Gremlin1/ Smad Pathway
por: Ruiqi, Liu, et al.
Publicado: (2021)

Dapagliflozin Attenuates Myocardial Fibrosis by Inhibiting the TGF-β1/Smad Signaling Pathway in a Normoglycemic Rabbit Model of Chronic Heart Failure
por: Chen, Xuefeng, et al.
Publicado: (2022)

Chlorogenic Acid Inhibits Liver Fibrosis by Blocking the miR-21-Regulated TGF-β1/Smad7 Signaling Pathway in Vitro and in Vivo
por: Yang, Fan, et al.
Publicado: (2017)

Key Role of the Endothelial TGF-β/ALK1/Endoglin Signaling Pathway in Humans and Rodents Pulmonary Hypertension
por: Gore, Benoît, et al.
Publicado: (2014)

ACPA Alleviates Bleomycin-Induced Pulmonary Fibrosis by Inhibiting TGF-β-Smad2/3 Signaling-Mediated Lung Fibroblast Activation
por: Chen, Dongxin, et al.
Publicado: (2022)

Labetalol and soluble endoglin aggravate bile acid retention in mice with ethinylestradiol-induced cholestasis
por: Cristina Igreja Sá, Ivone, et al.
Publicado: (2023)

Metformin Ameliorates Chronic Colitis-Related Intestinal Fibrosis via Inhibiting TGF-β1/Smad3 Signaling
por: Wang, Ying, et al.
Publicado: (2022)

Catalpol Protects Against Pulmonary Fibrosis Through Inhibiting TGF-β1/Smad3 and Wnt/β-Catenin Signaling Pathways
por: Yang, Fan, et al.
Publicado: (2021)

Fenofibrate Inhibits Subretinal Fibrosis Through Suppressing TGF‐β—Smad2/3 signaling and Wnt signaling in Neovascular Age‐Related Macular Degeneration
por: Chen, Qian, et al.
Publicado: (2020)

Follistatin Attenuates Myocardial Fibrosis in Diabetic Cardiomyopathy via the TGF-β–Smad3 Pathway
por: Wang, Yinhui, et al.
Publicado: (2021)

Wenfei Buqi Tongluo Formula Against Bleomycin-Induced Pulmonary Fibrosis by Inhibiting TGF-β/Smad3 Pathway
por: Ding, Lu, et al.
Publicado: (2022)

Mechanism of action of non-coding RNAs and traditional Chinese medicine in myocardial fibrosis: Focus on the TGF-β/Smad signaling pathway
por: Li, Chunjun, et al.
Publicado: (2023)

Shenkang Injection for Treating Renal Fibrosis-Metabonomics and Regulation of E3 Ubiquitin Ligase Smurfs on TGF-β/Smads Signal Transduction
por: Zou, Junju, et al.
Publicado: (2022)

Bellidifolin Ameliorates Isoprenaline-Induced Myocardial Fibrosis by Regulating TGF-β1/Smads and p38 Signaling and Preventing NR4A1 Cytoplasmic Localization
por: Yang, Hong-Xia, et al.
Publicado: (2021)

Atheroprone fluid shear stress-regulated ALK1-Endoglin-SMAD signaling originates from early endosomes
por: Mendez, Paul-Lennard, et al.
Publicado: (2022)

Rhubarb Protect Against Tubulointerstitial Fibrosis by Inhibiting TGF-β/Smad Pathway and Improving Abnormal Metabolome in Chronic Kidney Disease
por: Zhang, Zhi-Hao, et al.
Publicado: (2018)

Huangqi Shengmai Yin Ameliorates Myocardial Fibrosis by Activating Sirtuin3 and Inhibiting TGF-β/Smad Pathway
por: Pan, Jianheng, et al.
Publicado: (2021)

Regulation of TGF-β receptor hetero-oligomerization and signaling by endoglin
por: Pomeraniec, Leslie, et al.
Publicado: (2015)

Magnesium Isoglycyrrhizinate Ameliorates Fibrosis and Disrupts TGF-β-Mediated SMAD Pathway in Activated Hepatic Stellate Cell Line LX2
por: Tee, Jie Kai, et al.
Publicado: (2018)

Interleukin-19 Aggravates Pulmonary Fibrosis via Activating Fibroblast through TGF-β/Smad Pathway
por: Wang, Yu, et al.
Publicado: (2022)

Polyporus Polysaccharide Ameliorates Bleomycin-Induced Pulmonary Fibrosis by Suppressing Myofibroblast Differentiation via TGF-β/Smad2/3 Pathway
por: Jiang, Jintao, et al.
Publicado: (2020)

The Role of the TGF-β Coreceptor Endoglin in Cancer
por: Pérez-Gómez, Eduardo, et al.
Publicado: (2010)

Yougui Pills Attenuate Cartilage Degeneration via Activation of TGF-β/Smad Signaling in Chondrocyte of Osteoarthritic Mouse Model
por: Zhang, Lei, et al.
Publicado: (2017)

CFTR dysfunction increases endoglin and TGF‐β signaling in airway epithelia
por: Nicola, Teodora, et al.
Publicado: (2019)

Antibody-directed coupling of endoglin and MMP-14 is a key mechanism for endoglin shedding and deregulation of TGF-β signaling
por: Kumar, S, et al.
Publicado: (2014)

Induced Pluripotent Stem Cells Inhibit Bleomycin-Induced Pulmonary Fibrosis in Mice through Suppressing TGF-β1/Smad-Mediated Epithelial to Mesenchymal Transition
por: Zhou, Yan, et al.
Publicado: (2016)

GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition
por: Zhou, Xiao-Ming, et al.
Publicado: (2017)

Indole-3-propionic Acid-aggravated CCl(4)-induced Liver Fibrosis via the TGF-β1/Smads Signaling Pathway
por: Liu, Fei, et al.
Publicado: (2021)

P311 promotes renal fibrosis via TGFβ1/Smad signaling
por: Yao, Zhihui, et al.
Publicado: (2015)

PKC-ζ Aggravates Doxorubicin-Induced Cardiotoxicity by Inhibiting Wnt/β-Catenin Signaling
por: Cao, Yan-Jun, et al.
Publicado: (2022)

Potential Novel Prediction of TMJ-OA: MiR-140-5p Regulates Inflammation Through Smad/TGF-β Signaling
por: Li, Weihao, et al.
Publicado: (2019)

TGF-β1 induces peritoneal fibrosis by activating the Smad2 pathway in mesothelial cells and promotes peritoneal carcinomatosis
por: Lv, Zhi-Dong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_5lh98sl2l19aer1gn9ffqof79j