Fluoxetine treatment supports predictive validity of the three hit model of depression in male PACAP heterozygous mice and underpins the impact of early life adversity on therapeutic efficacy

According to the three hit concept of depression, interaction of genetic predisposition altered epigenetic programming and environmental stress factors contribute to the disease. Earlier we demonstrated the construct and face validity of our three hit concept-based mouse model. In the present work,...

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Detalles Bibliográficos
Autores principales: Gaszner, Tamás, Farkas, József, Kun, Dániel, Ujvári, Balázs, Berta, Gergely, Csernus, Valér, Füredi, Nóra, Kovács, László Ákos, Hashimoto, Hitoshi, Reglődi, Dóra, Kormos, Viktória, Gaszner, Balázs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537566/
https://www.ncbi.nlm.nih.gov/pubmed/36213293
http://dx.doi.org/10.3389/fendo.2022.995900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537566/
https://www.ncbi.nlm.nih.gov/pubmed/36213293
http://dx.doi.org/10.3389/fendo.2022.995900

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