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Simulation of the crosstalk between glucose and acetaminophen metabolism in a liver zonation model

The liver metabolizes a variety of substances that sometimes interact and regulate each other. The modeling of a single cell or a single metabolic pathway does not represent the complexity of the organ, including metabolic zonation (heterogeneity of functions) along with liver sinusoids. Here, we in...

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Detalles Bibliográficos
Autores principales: Maeda, Kazuhiro, Hagimori, Shuta, Sugimoto, Masahiro, Sakai, Yasuyuki, Nishikawa, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537759/
https://www.ncbi.nlm.nih.gov/pubmed/36210818
http://dx.doi.org/10.3389/fphar.2022.995597