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Simulation of the crosstalk between glucose and acetaminophen metabolism in a liver zonation model
The liver metabolizes a variety of substances that sometimes interact and regulate each other. The modeling of a single cell or a single metabolic pathway does not represent the complexity of the organ, including metabolic zonation (heterogeneity of functions) along with liver sinusoids. Here, we in...
Autores principales: | Maeda, Kazuhiro, Hagimori, Shuta, Sugimoto, Masahiro, Sakai, Yasuyuki, Nishikawa, Masaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537759/ https://www.ncbi.nlm.nih.gov/pubmed/36210818 http://dx.doi.org/10.3389/fphar.2022.995597 |
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