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PTEN is recognized as a prognostic-related biomarker and inhibits proliferation and invasiveness of skull base chordoma cells

OBJECTIVE: This work aimed to examine the function of phosphatase and tensin homologue deleted on chromosome 10 (PTEN) in skull base chordoma (SBC) at the clinical and cellular levels. METHODS: Totally 65 paraffin-embedded and 86 frozen specimens from 96 patients administered surgery were analyzed....

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Detalles Bibliográficos
Autores principales: Tian, Kaibing, Ma, Junpeng, Wang, Ke, Li, Da, Zhang, Junting, Wang, Liang, Wu, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537766/
https://www.ncbi.nlm.nih.gov/pubmed/36211273
http://dx.doi.org/10.3389/fsurg.2022.1011845