Cargando…

Characterization of cancer-related fibroblasts (CAF) in hepatocellular carcinoma and construction of CAF-based risk signature based on single-cell RNA-seq and bulk RNA-seq data

BACKGROUND: Cancer-associated fibroblasts (CAFs) are involved in tumor growth, angiogenesis, metastasis, and resistance to therapy. We sought to explore the CAFs characteristics in hepatocellular carcinoma (HCC) and establish a CAF-based risk signature for predicting the prognosis of HCC patients. M...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Lianghe, Shen, Ningjia, Shi, Yan, Shi, Xintong, Fu, Xiaohui, Li, Shuang, Zhu, Bin, Yu, Wenlong, Zhang, Yongjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537943/
https://www.ncbi.nlm.nih.gov/pubmed/36211448
http://dx.doi.org/10.3389/fimmu.2022.1009789