eIF4G1 N-terminal intrinsically disordered domain is a multi-docking station for RNA, Pab1, Pub1, and self-assembly

Yeast eIF4G1 interacts with RNA binding proteins (RBPs) like Pab1 and Pub1 affecting its function in translation initiation and stress granules formation. We present an NMR and SAXS study of the N-terminal intrinsically disordered region of eIF4G1 (residues 1–249) and its interactions with Pub1, Pab...

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Detalles Bibliográficos
Autores principales: Chaves-Arquero, Belén, Martínez-Lumbreras, Santiago, Sibille, Nathalie, Camero, Sergio, Bernadó, Pau, Jiménez, M. Ángeles, Zorrilla, Silvia, Pérez-Cañadillas, José Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537944/
https://www.ncbi.nlm.nih.gov/pubmed/36213119
http://dx.doi.org/10.3389/fmolb.2022.986121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9537944/
https://www.ncbi.nlm.nih.gov/pubmed/36213119
http://dx.doi.org/10.3389/fmolb.2022.986121

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