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Herpes simplex virus type 2 inhibits TNF-α-induced NF-κB activation through viral protein ICP22-mediated interaction with p65

Herpes simplex virus type 2 (HSV-2) is a prevalent human pathogen and the main cause of genital herpes. After initial infection, HSV-2 can establish lifelong latency within dorsal root ganglia by evading the innate immunity of the host. NF-κB has a crucial role in regulating cell proliferation, infl...

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Detalles Bibliográficos
Autores principales: Hu, Huimin, Fu, Ming, Li, Chuntian, Zhang, Binman, Li, Yuncheng, Hu, Qinxue, Zhang, Mudan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538160/
https://www.ncbi.nlm.nih.gov/pubmed/36211339
http://dx.doi.org/10.3389/fimmu.2022.983502