Adenoviral delivery of soluble ovine OX40L or CD70 costimulatory molecules improves adaptive immune responses to a model antigen in sheep

The tumour necrosis factor superfamily OX40L and CD70 and their receptors are costimulatory signalling axes critical for adequate T and B cell activation in humans and mice. In this work we inoculated groups of sheep with human recombinant adenovirus type 5 (Ad) expressing Ovis aries (Oa)OX40L or Oa...

Descripción completa

Detalles Bibliográficos
Autores principales: Rojas, José M., Mancho, Carolina, Louloudes-Lázaro, Andrés, Rodríguez-Martín, Daniel, Avia, Miguel, Moreno, Santiago, Sevilla, Noemí, Martín, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538494/
https://www.ncbi.nlm.nih.gov/pubmed/36211974
http://dx.doi.org/10.3389/fcimb.2022.1010873

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538494/
https://www.ncbi.nlm.nih.gov/pubmed/36211974
http://dx.doi.org/10.3389/fcimb.2022.1010873

Ejemplares similares