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A universal SARS‐CoV DNA vaccine inducing highly cross‐reactive neutralizing antibodies and T cells

New variants in the SARS‐CoV‐2 pandemic are more contagious (Alpha/Delta), evade neutralizing antibodies (Beta), or both (Omicron). This poses a challenge in vaccine development according to WHO. We designed a more universal SARS‐CoV‐2 DNA vaccine containing receptor‐binding domain loops from the hu...

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Detalles Bibliográficos
Autores principales: Appelberg, Sofia, Ahlén, Gustaf, Yan, Jingyi, Nikouyan, Negin, Weber, Sofie, Larsson, Olivia, Höglund, Urban, Aleman, Soo, Weber, Friedemann, Perlhamre, Emma, Apro, Johanna, Gidlund, Eva‐Karin, Tuvesson, Ola, Salati, Simona, Cadossi, Matteo, Tegel, Hanna, Hober, Sophia, Frelin, Lars, Mirazimi, Ali, Sällberg, Matti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538582/
https://www.ncbi.nlm.nih.gov/pubmed/35986481
http://dx.doi.org/10.15252/emmm.202215821