FGFR4-Targeted Chimeric Antigen Receptors Combined with Anti-Myeloid Polypharmacy Effectively Treat Orthotopic Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common soft tissue cancer in children. Treatment outcomes, particularly for relapsed/refractory or metastatic disease, have not improved in decades. The current lack of novel therapies and low tumor mutational burden suggest that chimeric antigen receptor (CAR) T-c...

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Detalles Bibliográficos
Autores principales: Sullivan, Peter M., Kumar, Rajesh, Li, Wei, Hoglund, Virginia, Wang, Lingyan, Zhang, Yue, Shi, Megan, Beak, Dusan, Cheuk, Adam, Jensen, Michael C., Khan, Javed, Dimitrov, Dimiter S., Orentas, Rimas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Models and Technologies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538595/
https://www.ncbi.nlm.nih.gov/pubmed/35877472
http://dx.doi.org/10.1158/1535-7163.MCT-22-0059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538595/
https://www.ncbi.nlm.nih.gov/pubmed/35877472
http://dx.doi.org/10.1158/1535-7163.MCT-22-0059

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