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SARS‐CoV‐2 spike protein aggregation is triggered by bacterial lipopolysaccharide

SARS‐CoV‐2 spike (S) protein is crucial for virus invasion in COVID‐19. Here, we showed that lipopolysaccharide (LPS) can trigger S protein aggregation at high doses of LPS and S protein. We demonstrated the formation of S protein aggregates by microscopy analyses, aggregation and gel shift assays....

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Detalles Bibliográficos
Autores principales: Petrlova, Jitka, Samsudin, Firdaus, Bond, Peter J., Schmidtchen, Artur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538650/
https://www.ncbi.nlm.nih.gov/pubmed/36050806
http://dx.doi.org/10.1002/1873-3468.14490