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High-Throughput Human Complement C3 N-Glycoprofiling Identifies Markers of Early Onset Type 1 Diabetes Mellitus in Children

Recently, it was shown that children at the onset of type 1 diabetes (T1D) have a higher proportion of oligomannose glycans in their total plasma protein N-glycome compared to their healthy siblings. The most abundant complement component, glycoprotein C3, contains two N-glycosylation sites occupied...

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Detalles Bibliográficos
Autores principales: Šoić, Dinko, Keser, Toma, Štambuk, Jerko, Kifer, Domagoj, Pociot, Flemming, Lauc, Gordan, Morahan, Grant, Novokmet, Mislav, Gornik, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538898/
https://www.ncbi.nlm.nih.gov/pubmed/36031042
http://dx.doi.org/10.1016/j.mcpro.2022.100407