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In vitro biotransformation assays using fish liver cells: Comparing rainbow trout and carp hepatocytes

Biotransformation assays using primary hepatocytes from rainbow trout, Oncorhynchus mykiss, were validated as a reliable in vitro tool to predict in vivo bioconcentration factors (BCF) of chemicals in fish. Given the pronounced interspecies differences of chemical biotransformation, the present stud...

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Detalles Bibliográficos
Autores principales: Bischof, Ina, Arnot, Jon A., Jürling, Heinrich, Knipschild, Georg, Schlechtriem, Christian, Schauerte, Anna, Segner, Helmut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538944/
https://www.ncbi.nlm.nih.gov/pubmed/36211196
http://dx.doi.org/10.3389/ftox.2022.1021880