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In vitro biotransformation assays using fish liver cells: Comparing rainbow trout and carp hepatocytes
Biotransformation assays using primary hepatocytes from rainbow trout, Oncorhynchus mykiss, were validated as a reliable in vitro tool to predict in vivo bioconcentration factors (BCF) of chemicals in fish. Given the pronounced interspecies differences of chemical biotransformation, the present stud...
Autores principales: | Bischof, Ina, Arnot, Jon A., Jürling, Heinrich, Knipschild, Georg, Schlechtriem, Christian, Schauerte, Anna, Segner, Helmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9538944/ https://www.ncbi.nlm.nih.gov/pubmed/36211196 http://dx.doi.org/10.3389/ftox.2022.1021880 |
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