Urolithin A targets the AKT/WNK1 axis to induce autophagy and exert anti-tumor effects in cholangiocarcinoma

Urolithin A (UA; 3,8-dihydroxybenzo[c]chromen-6-one), a metabolite generated by intestinal bacteria during the biotransformation of ellagitannins, has gained considerable attention in treating several cancers. Cholangiocarcinoma (CCA) remains one of the most lethal cancers; it grows in a special env...

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Detalles Bibliográficos
Autores principales: Sahashi, Hidenori, Kato, Akihisa, Yoshida, Michihiro, Hayashi, Kazuki, Naitoh, Itaru, Hori, Yasuki, Natsume, Makoto, Jinno, Naruomi, Kachi, Kenta, Asano, Go, Toyohara, Tadashi, Kito, Yusuke, Ammanamanchi, Sudhakar, Kataoka, Hiromi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539031/
https://www.ncbi.nlm.nih.gov/pubmed/36212467
http://dx.doi.org/10.3389/fonc.2022.963314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539031/
https://www.ncbi.nlm.nih.gov/pubmed/36212467
http://dx.doi.org/10.3389/fonc.2022.963314

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