Inhibition of PSD95‐nNOS protein–protein interactions decreases morphine reward and relapse vulnerability in rats

Glutamate signalling through the N‐methyl‐d‐aspartate receptor (NMDAR) activates the enzyme neuronal nitric oxide synthase (nNOS) to produce the signalling molecule nitric oxide (NO). We hypothesized that disruption of the protein–protein interaction between nNOS and the scaffolding protein postsyna...

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Detalles Bibliográficos
Autores principales: Oliva, Idaira, Saberi, Shahin A., Rangel‐Barajas, Claudia, Iyer, Vishakh, Bunner, Kendra D., Lai, Yvonne Y., Kulkarni, Pushkar M., Garai, Sumanta, Thakur, Ganesh A., Crystal, Jonathon D., Rebec, George V., Hohmann, Andrea G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539577/
https://www.ncbi.nlm.nih.gov/pubmed/36001441
http://dx.doi.org/10.1111/adb.13220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539577/
https://www.ncbi.nlm.nih.gov/pubmed/36001441
http://dx.doi.org/10.1111/adb.13220

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