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Inhibition of PSD95‐nNOS protein–protein interactions decreases morphine reward and relapse vulnerability in rats
Glutamate signalling through the N‐methyl‐d‐aspartate receptor (NMDAR) activates the enzyme neuronal nitric oxide synthase (nNOS) to produce the signalling molecule nitric oxide (NO). We hypothesized that disruption of the protein–protein interaction between nNOS and the scaffolding protein postsyna...
Autores principales: | Oliva, Idaira, Saberi, Shahin A., Rangel‐Barajas, Claudia, Iyer, Vishakh, Bunner, Kendra D., Lai, Yvonne Y., Kulkarni, Pushkar M., Garai, Sumanta, Thakur, Ganesh A., Crystal, Jonathon D., Rebec, George V., Hohmann, Andrea G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539577/ https://www.ncbi.nlm.nih.gov/pubmed/36001441 http://dx.doi.org/10.1111/adb.13220 |
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