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Liraglutide treatment attenuates inflammation markers in the cardiac, cerebral and renal microvasculature in streptozotocin‐induced diabetic rats

BACKGROUND: Diabetes mellitus (DM) induces cardiac and cerebral microvascular dysfunction via increased glycation, oxidative stress and endothelial activation. Liraglutide, a glucagon‐like peptide‐1 analogue, inhibited NOX2 and adhesion molecules in isolated endothelial cells. Here, we have studied...

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Detalles Bibliográficos
Autores principales: Baylan, Umit, Korn, Amber, Emmens, Reindert W., Schalkwijk, Casper G., Niessen, Hans W. M., Krijnen, Paul A. J., Simsek, Suat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9539594/
https://www.ncbi.nlm.nih.gov/pubmed/35488737
http://dx.doi.org/10.1111/eci.13807